S.No Panel PlaceHolder 1What tag rendered in output ?Panel will render Div tags in the browerWhat tag rendered in output ?PlaceHolder will not render any tags 2Does it provide Styling Attributes ?Panel have the styling capabilites, so we can set the cssclass or style properties such as background-color, forecolor etc..Does it provide Styling Attributes ?Placeholder does not have any style attributes associated. We can not set cssclass or forecolor etc... 3Automatic Width Adjustment: Panel cannot adjust width automatically if controls are added in it.Automatic Width Adjustment: PlaceHolder can adjust width automatically if controls are added in it. 4Memory Size: Panel is heavy in memory size as compare to PlaceHolderMemory Size:PlaceHolder is light in memory size as compare to Panel. 5When to use ? If we want to use it to separate controls visually, then we have to use Panel control.When to use ? If we just want a container, without all the Display properties, then we have to use PlaceHolder control.
Panel vs PlaceHolder
Difference between Panel and PlaceHolder